Restorative effects of Radix Notoginseng on hepatic lesions provoked by CCl4 in experimental mice [Tác dụng hồi phục các tổn thương gan gây ra bởi CCl4 của củ tam thất trên chuột thực nghiệm] / Dương Thị Ly Hương,Nguyễn Trần Giáng Hương,Phạm Xuân Sinh // TC Dược học . -2003. -p. 38-41. -(Vietnamese). -ISSN 0866-7225.
Classification (rubrics): 34.45.05
Key words: Radix notoginseng; Hepatic lesions; Mices; Restoration;
Location: TVKHKTTW, CVv 13
Classification (rubrics): 34.45.05
Key words: Radix notoginseng; Hepatic lesions; Mices; Restoration;
The experimental results showed that the oral administration of Radix Notoginseng (RD) with the dose of 5g/kg body weight exhibited the moderate recovering effect on CCl4-induced liver injuries in rats. Although the serum ASAT concentration in CCl4-intoxicated and RD-treated group was still higher than that of control-normal group after one day, it was significantly lower than that of intoxicated and non treated group (p<0.01). There were no differences in ALAT concentration between RD-and CCl4-treated groups in that day. The four days treatment with Radix Notoginseng has reduced the concentrations of both ASAT and ALAT to normal levels while ASAT in CCl4-intoxicated rats was still higher.
Location: TVKHKTTW, CVv 13
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