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Assessment of stock process in national business during period 1999-2003

Influence of extract from fruit of Garcinia cambogia on anti-oxydative enzymes of liver in chronic intoxicated rat by CCI4

To determine the effect of G. cambogia fruit extract on CCI4 induced liver rats, in the report, G. cambogia (dose: 85 mg/10g weight body) given for 7 days on the chronic CCI4 liver damage were studied. G. cambogia treatment completely prevented all the damaged- changes observed in CCI4- chronic rats. Treatment G. cambogia extract enzyme SOD activity significantly increased 11% comparing with CCI4 treatment rats and 30% with control ones. The imbalance in lipid metabolism could be the reason for increase in lipide peroxidation. When rats were treated with G. cambogia, the showed that there were significantly inhibited the rise in (MDA) lipide peroxidase and weight loss, which is evident from the improved antioxidant status. The present study is an attempt to elucidate the antiperoxidative proprty of G. cambogia CCI4 induced damage liver in rats and its effically to inhibit lipid peroxidation.

Investigation of bioavailability and biological equivalence of 3 amoxicillin products

The study was carried out on 18 healthy volunteers of both sexes (9 males and 9 females). Each subject received three different treatment regimens of amoxicillin according to a randomized, cross over design: one 500 mg tablet t.id., one 500 mg capsule t.i.d, or one 1,000 mg tablet b.i.d.. Plasma concentrations of amoxicillin were measured by HPLC. The comparison between 500 mg capsules and 500 mg tablets did not disclose any important differences in AUC (O-inf) and Cmax' whereas it detected a significant difference in Tmax (1.3 % 0.2 h with the tablet versus 1.8 % 0.2 h with the capsule). Treatment with 1,000 mg tablets was associated with higher values of Cmax and AUC(O-inf) than with the two 500 mg formulations with the 500 mg tablet and with the 500 mg capsule and with a delayed Tmax (2.3 :!: 0.4 h). The treatment regimen based on one 500 mg tablet t.id. ensures more rapid absorption than the treatment regime based on one 500 mg capsule t.i.d. However, AUCs and Cmax values are not significantly different.

Isolation and structural identification of cucurbitacine glycoside components from seeds of Momordica charantia L.

Two triterpen glycoside, Momordicoside A and Momordicoside B were isolated from the defatted seeds of Momordica charantia L. (Cucurbitaceae). Their structures were determined on the basis of spectra including FAB-HR Mass, 1H-NMR, 13C-NMR, DEPT, HMQC, HMBC and comparision with published data. Momordicoside A and Momordicoside B were ecucidated as 3-0-beta-gentiobioside and (3-0-beta-D-xylopyranosyl (1-4)- {Beta-D-glucopyranosyl (1-6)] - beta-D-glucopyranoside, respectively, of cucurbit-5-en-3beta, 22 (S),23 (R), 24 (R),25 - pentaol.

Study on influence of manufacture on chemical composition of Rhizoma Polygonati

The chemical composition of Rhizoma Polygonati was investigated. The results showed that Rhizoma Polygonati contained flavonoid, alcaloid, sterol, sugar, iridoid glycosid, amino acid and fat. After processing, Rhizoma Polygonati were decreased effect causing itch. Content of sugar, amino acid were increased. On TLC, two spots of alcaloid , one spot of flavonoid were increased.

Study on influence of some additifs on stability of eye drops with vitamine B5

Study on membrane enveloping pellet of chlorpheniramine SR

Effects of membrance components on the release of chlorpheniramine from pellet were studied. The optimal formula of membrance containing ethylcellulose were established. This membrance could prolong release of chlorpheniramine quite constantly from pellet up to 8 hours.